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1 | RAMS-2.3.0.zip\RAMS-2.3.0\OnlineHelp\ACORP | ACORP_App8Instructions.docx | Thu May 17 00:38:54 2018 UTC |
2 | RAMS-2.3.0.zip\RAMS-2.3.0\OnlineHelp\ACORP | ACORP_App8Instructions.docx | Tue Jul 17 21:22:09 2018 UTC |
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1 | Instructio ns for Com pletion of the | |
2 | ACORP Appe ndix 8 -- Use of Exp losive Age nt(s) | |
3 | within the VMU or in Animals | |
4 | (ACORP App . 8 Instru ctions) | |
5 | Version 4 | |
6 | ||
7 | These inst ructions p rovide det ailed guid ance on co mpleting A ppendix 8 of the ACO RP, and ar e referenc ed to the numbers of the items in Append ix 8. ONLY complete this appen dix if it is relevan t to the p rotocol be ing submit ted for re view. The PI may use the ACORP Appendix 8 template provided in the RAM S applicat ion by usi ng the lin k availabl e in quest ion 16 of section M. | |
8 | ||
9 | General In structions : | |
10 | Answer eac h question by comple ting the t able provi ded or ent ering the requested informatio n at the ► . Enter “N /A” for an y item tha t does not apply to this proto col. The sections o f the form will expa nd as need ed. | |
11 | To check a n item, ty pe “X” ins ide the ( ) provid ed. | |
12 | Define eac h abbrevia tion the f irst time it is used . | |
13 | ||
14 | Header for Every Pag e. The he ader infor mation for this appe ndix is pr e-populate d to match header fo r the Main Body of t he ACORP t o which it applies, to identif y each pag e of this Appendix w ith that A CORP: | |
15 | PI’s last name: The PI’s name is prepopu lated | |
16 | Protocol N o. Assigne d by the I ACUC – Thi s is a uni que identi fier for e ach protoc ol that is automatic ally gener ated by th e system t o the prot ocol as a whole | |
17 | ||
18 | Official D ate of App roval – Th is is the date of fi nal and un equivocal approval b y the IACU C, as defi ned in the PHS Assur ance, whic h determin es the due dates of the first annual con tinuing re view and t he trienni al de novo review, a s applicab le. The IA CUC commit tee will e nter this date into the form w hen a deci sion is ma de. | |
19 | ||
20 | Full name( s) of Prin cipal Inve stigator(s ). Give t he full na me(s) of t he Princip al Investi gator(s), who are re sponsible for the us e of anima ls on this protocol. | |
21 | ||
22 | Explosive agents to be used. Identify e ach explos ive agent to be used on this p rotocol, e ither with in the ani mal facili ty (regard less of wh ether the agents wil l be admin istered to animals) or adminis tered to a nimals (re gardless o f where th e administ ration to the animal s will be performed) . | |
23 | ||
24 | Identify t he explosi ve agents – Give all names use d in this ACORP to r efer to ea ch agent, then descr ibe the MS DS on file for each agent, inc luding the primary n ame of the agent sho wn on the MSDS, the CAS regist ry number for the ag ent, and t he locatio n of the M SDS on fil e. | |
25 | ||
26 | Locations where the explosive agents wil l be used – Identify the build ing(s) and room numb er(s) wher e each of the agents will be u sed, indic ating whet her each l ocation is within th e VMU or o utside of the VMU. | |
27 | ||
28 | Procedure( s) to be p erformed – The use o f explosiv e agents i n the anim al researc h facility is prohib ited unles s the IACU C and the Subcommitt ee on Rese arch Safet y (SRS) gr ant local approval. That appro val should only be g ranted und er excepti onal circu mstances, when scien tific reas ons preclu de the use of non-ex plosive al ternatives . Describ e the reas ons that t his use of explosive agents sh ould be ap proved. | |
29 | ||
30 | Precaution s to be ta ken to pre vent explo sions – Be fore appro ving the A CORP, the IACUC must ensure th at all rea sonable pr ecautions to prevent explosion s are to b e taken. T hese preca utions gen erally inc lude, but need not b e limited to, the fo llowing: | |
31 | ||
32 | Use of the agents on ly within a properly operating , ventilat ed safety hood. | |
33 | Locating a nd powerin g outside the hood a ny electri cal equipm ent to be used with such agent s. | |
34 | Storage on ly in an e xplosion-p roof refri gerator or freezer. | |
35 | Provisions to ensure that all potentiall y explosiv e fumes ha ve dissipa ted from a nimal carc asses and other obje cts before they are placed int o storage. | |
36 | No disposa l of empty container s or other items con taining tr aces of an y explosiv e agent by incinerat ion or in receptacle s for wast e that is ordinarily incinerat ed. | |
37 | ||
38 | Period of use. Defi ne the per iod of tim e over whi ch the exp losive age nt(s) may be used, b y specifyi ng the ear liest and latest dat es on whic h they may be used: | |
39 | ||
40 | Animals th at will be administe red explos ive agents – Describ e any anim als that w ill be adm inistered any of the explosive agents li sted in It em 2.a, ab ove, notin g the spec ies, the r ange of av erage weig hts of ind ividual an imals to b e treated, and the a pproximate number of animal su bjects tha t will be administer ed the exp losive age nt(s). No te that an y explosiv e agents t o be admin istered to animals o n this pro tocol must also be d ocumented in Appendi x 3. | |
41 | ||
42 | Personnel. Identify each indi vidual who will hand le any of the explos ive agents as part o f this pro tocol, and describe the indivi dual’s tra ining and experience with rega rd to use of explosi ve agents. Note th at any of these indi viduals wh o will be involved i n administ ering any of the exp losive age nt(s) to a nimals mus t also be included i n Item E o f the main body of t he ACORP. | |
43 | ||
44 | Signatures . Provide the signa tures requ ired on th e signatur e pages (I tem Z.8) o f the main body of t his ACORP. |
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