Supplement Application and Submission Instructions

The Co-Principal Investigator (PI)/Study Chair (SC) must use this form to submit as a supplement to the Principal Investigator/Study Chair New Project Application to the VA Central IRB. The Co-PI/SC's Supervisor and ACOS/R&D or Chief of Staff of the Co-PI/SC's site also must complete a portion of this form. When submitting a revised VA Central IRB Form 108, only the signature of the PI/SC who signed the original Form 108 is needed. This form does not need to be resubmitted. It is only re-submitted if something on this form changes. The Co-PI may sign amendment requests if the PI/SC who signed the 108 is not available. Ensure the version number and date are included for all revisions. Upon completion of this form, it should be appended to the VA Central IRB Form, PI/SC New Project Application and submitted with the rest of the application package.