The In-Center Hemodialysis Option

Hemodialysis (HD) is one way to replace the function of kidneys that don’t work. HD is most often done in a clinic in one of two ways:

It is sometimes called “in-center” HD.

a chair in a dialysis clinic

Hemodialysis Access

All HD requires a way to take blood out of the body to be cleaned, and then put it back in. This is called a vascular access, or just access. There are three types of access:

A fistula is the safest type, if you can have one.

hemodialysis access in patient's left arm

HD Access: Fistulas

Dialysis needs the strong blood flow of an artery (the blood vessels that carry blood away from the heart). But veins (the blood vessels that carry blood to the heart) are closer to the surface of your skin and easier to reach. Linking an artery to a vein gives you the best of both: strong blood flow that is easy to reach.

Some ways of linking the artery and vein to make an access for HD are better than others. A fistula connects your artery directly to your vein. A graft connects an artery to a vein with a piece of man-made vein.

Fistulas can last the longest (sometimes decades) and they have the least chance of developing blood clots or infections that could put you in the hospital. If you want to do HD, a fistula is ideal. Plan ahead! A fistula needs to be made at least a few months before dialysis starts, so it has time to “mature” and be ready to use. It is wise to get a fistula made about 6 months before you need to start HD.

graft and fistula diagrams

HD Access: Catheters

HD catheters are plastic tubes that are placed in a large vein in the neck, chest, or groin. They are used if someone needs dialysis right away, or has no other choice. A catheter is partly out of your body and partly inside your blood vessels. The tip is in your heart.

Catheters have several problems:

diagram of catheter and animation of germs entering the bloodstream through the catheter

HD Cleans Your Blood Outside Your Body

When you do HD, two needles are placed in your access. A nurse or technician connects the needles to tubing that carries your blood to a dialyzer, or artificial kidney. The dialyzer has filters inside to clean your blood. Wastes and extra water are removed, and then your cleaned blood comes back to you. A blood pump pushes your blood through the tubing at a rate that your doctor prescribes.

dialysis machine

3 Days or 3 Nights a Week

HD in a center can be done in two ways:

hemodialysis access

Keeping Your Body in Balance

The job of healthy kidneys is to keep substances in your blood in balance. The closer to balance a treatment for kidney failure brings you, the better you may feel. When you feel better, you can do more of what matters to you. Nocturnal HD in a center gives you about twice as much treatment as standard HD

two equal weighted balls balanced on a bar

Standard HD: Big Ups & Downs

Between dialysis treatments, wastes and excess water build up in your blood. If you have a 4-hour treatment on Mondays, Wednesdays, and Fridays, you have no treatment on Tuesdays, Thursdays, Saturdays, or Sundays. The ups and downs when wastes and water build up are big with standard in-center HD—and they are hard on the heart. Heart problems are the leading cause of death in people on dialysis. High blood pressure or diabetes, the two main causes of kidney failure, also affect the heart. Most sudden death on dialysis happens after a 2-day weekend with no treatment. Forms of dialysis that are done more often are more gentle on your heart.

graph showing the ups and downs of fluid and waste in the body when doing 3x/week dialysis

Nocturnal HD: Very Small Ups & Downs

Nocturnal HD in a center removes much more water and wastes from your blood than standard HD. And, since the treatments are twice as long, it is much more gentle, as you can see from the very small spikes in water and wastes (green) in the picture on the right.

This means that even with three treatments per week, you may feel good from day to day, with fewer symptoms from kidney failure. In fact, most people feel like themselves again about 10 minutes after doing a nocturnal HD treatment.

graph showing the much smaller ups and downs fluid and waste in the body when doing nocturnal dialysis

In-center HD and Your Lifestyle

Now that we’ve seen the basics of how in-center HD works, let’s look at how it might affect your life in the areas of:

family portrait on front steps of home

Standard HD and What You Eat

Since standard HD is done 3 times a week for only 4 hours, it requires more strict diet and fluid limits than any other option. Your dietitian will go over your lab test results with you each month and help you come up with a plan that includes as many of your favorite foods as possible. To learn more about lab tests, visit the Laboratory.

Nocturnal HD in a clinic is done 3 times a week for about 8 hours. More treatment means you have fewer diet and fluid limits. You can eat more of what you like best with this treatment option.

grilled chicken and vegetables on a skewer

Standard HD Means Limits on Some Foods & Fluids

Most people who do HD must limit their intake of:

If you have diabetes, you still need to limit starchy foods.

If you choose standard in-center treatment, you MUST follow the strict limits to feel your best. If an unrestricted diet is important to you, talk with your care team about other dialysis options that have fewer limits.

foods that might be off limits for dialysis patients, with flashing warning symbol

Standard HD and Medications

If you choose standard HD, you may need to take as many as 19 pills each day. Most people on standard in-center need phosphate binders and blood pressure pills. You may also need erythropoietin EPO to help treat anemia. Anemia is a shortage of oxygen-carrying red blood cells. It can leave you feeling tired, weak, and cold. If you have diabetes or other health problems, you will still need to take prescribed drugs for them, though the dose may change when your kidneys don’t work.

If you do nocturnal HD in a clinic, you may need fewer—or no—phosphate binders or blood pressure pills. You may need EPO to help treat anemia, but may be able to use a lower dose. If you have diabetes or other health problems, you will still need to take prescribed drugs for them, though the dose may change when your kidneys don’t work

pill box

Standard HD and Your Schedule

If you do standard in-center HD, the clinic will work with you to assign a time slot. Your treatments will be done at the same time on Mondays, Wednesdays, and Fridays or Tuesdays, Thursdays, and Saturdays. If the time slot you are given is not a good fit for your life, your job, your childcare, or your ride to the clinic, talk to your care team.

alarm clock

Standard HD and Your Job

Do you want to be able to work? A work-friendly treatment:

Standard in-center HD is not very work-friendly for all of these reasons. It takes time out of the day, when most people need to be at work. It can cause symptoms that make it hard to work, and can lead to more hospital stays than other treatment options. People DO work on standard in-center HD—but it is more of a challenge than it would be with other treatment options

co-workers in a meeting room

Standard HD and Travel

When you do HD in a center—during the day or at night—you can travel by finding a clinic at your destination that has a time slot open and can take you. This is best done a few months before you want to travel. Your social worker can help you plan and send the clinic your medical records. You will need to be up-to-date with your vaccines, too.

street signs pointed in various directions

Standard HD, Fertility, and Your Sex Life

Standard HD, Fertility, and Your Sex Life

People who do standard in-center HD report more problems with sexuality and fertility than those who do any other treatment option. For men, about half who do this treatment report problems with erections. It is also more difficult to father a child.

Women have problems, too. It is harder to carry a child using this treatment option. Women who become pregnant on standard in-center HD may have a chance of carrying a baby to term if they do longer and/or more frequent treatments.

There are few studies on the sexuality of people who do nocturnal HD treatments. People who do dialysis this way say they feel better, and there are some reports of women being able to carry babies to term.

happy family photo of mom, dad, and young son

Standard HD: Facts to Consider

There are things to think about when you do HD in a clinic—during the day or at night. Your risk of infection is very high if you start treatment with a catheter. If you know you want to do HD, get a fistula or graft well ahead of time.

You need to be at the clinic for each treatment at the time that is set for you. If this time is not a good fit for your life, talk to your care team. You may be able to switch to a time that fits better, or to a clinic that has a better time for you. You may have to wait until the time slot you want opens up. Don’t miss any dialysis! Missed treatment time can cost you your life when you are on dialysis.

Some people have a hard time sleeping in a clinic at night. Wearing earplugs and a sleep mask may help. Some even bring in a foam pad for the chair to make it easier to sleep.

dialysis machine

Dealing with HD Needles

Fistulas and grafts for HD use needles. If needles bother you, there are lots of things you can do to help:

porcupine