COMS Pilot Program Code The proof of concept Chemotherapy Ordering Management System (COMS) was developed with funding from the VA Center for Innovation (VACI) in the 2010 employee Innovations competition. The COMS application supports oncology healthcare teams in ordering, preparing, and documenting the administration through five (5) clinical modules and read/write interoperability with Veterans Health Information Systems and Technology Architecture (VistA). The COMS application satisfies the unique needs of chemotherapy ordering and standardizes capabilities to meet direct entry of chemotherapy order consistent with oncology practice. COMS interfaces and interacts with existing applicable Veterans Health Administration (VHA) health care systems, modules, and processes with Computerized Patient Record System (CPRS) and VistA databases. As an open source, systems agnostic solution, COMS is a user-facing, patient-centric solution not restrained by Commercial-off-the-Shelf (COTS) product limitations. It is a Web-based application consisting of Hypertext Precursor (PHP), Java Script, Simple Object Access Protocol (SOAP), and Representational state transfer (RESTful) Web services.