The Clinical Case Registries (CCR) application collects data on the population of veterans with certain clinical conditions, namely Hepatitis C and Human Immunodeficiency Virus (HIV) infection. This version of the CCR software has been significantly redesigned to provide access to the HIV Case Registry (CCR:HIV) and Hepatitis C Case Registry (CCR:HEPC) from a single interface. Data from the registries is used for both clinical and administrative reporting on both a local and national level. Each facility can produce local reports (information related to patients seen in their system). Reports from the national database are used to monitor clinical and administrative trends, including issues related to patient safety, quality of care, and disease evolution across the national population of patients. The software uses pre-defined selection rules that identify patients with possible Hepatitis C and/or HIV (such as a disease related ICD-9/ICD-10 code or a positive result on an antibody test) and adds them to the registry in a pending state. Pending patients are reviewed by the local registry coordinator and if the data confirms the diagnosis, the local registry coordinator confirms the patient in the registry. A nightly background process transmits a set of predefined data via HL7 to the national CCR database at the Austin Information Technology Center (AITC) managed by the VHA Center for Quality Management in Public Health (CQMPH). Data from both registries is aggregated in the same message. The CCR software creates a limited set of database elements to be stored locally in the VistA system, and focuses on assuring that the local listing is complete and accurate, that the desired data elements are extracted, and that data elements are appropriately transmitted to the national database. 